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Table 3 Interrelation of c-met, E-cad and Sdc1 expression in DCIS and correlation with histopathological characteristics

From: An expression signature of syndecan-1 (CD138), E-cadherin and c-met is associated with factors of angiogenesis and lymphangiogenesis in ductal breast carcinoma in situ

 

c-met

E-cad

Sdc1

 

Negative (n = 73)

Positive (n = 69)

P

Negative (n = 48)

Positive (n = 101)

P

Negative (n = 42)

Positive (n = 105)

P

c-met positive

0.0%

100.0%

 

30.8%

58.8%

0.004

38.2%

56.3%

0.071

E-cad positive

56.5%

80.6%

0.004

0.0%

100.0%

 

51.4%

76.0%

0.007

Sdc1 positive

66.7%

80.6%

0.071

58.5%

80.9%

0.007

0.0%

100.0%

 

High grade DCIS

47.2%

48.5%

0.877

47.9%

47.5%

0.960

37.5%

49.5%

0.193

ER positive

25.4%

31.3%

0.463

20.0%

31.5%

0.176

37.1%

26.0%

0.251

PR positive

33.9%

37.9%

0.643

37.8%

33.7%

0.655

40.0%

31.6%

0.368

ErbB2 positive

12.5%

27.3%

0.044

23.5%

23.9%

0.964

11.8%

28.0%

0.057

  1. DCIS, ductal carcinoma in situ; E-cad, E-cadherin; ER, oestrogen receptor; PR, progesterone receptor; Sdc, syndecan.