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Table 1 Selected characteristics among breast cancer cases by hormone receptor status: SEER program, 1990–2001

From: Hormone receptor status, tumor characteristics, and prognosis: a prospective cohort of breast cancer patients

  ER+PR+ ER+PR- ER-PR+ ER-PR-
  (n = 98,463) (n = 19,886) (n = 4,896) (n = 31,930)
Characteristics n Column % Row % n Column % Row % n Column % Row % n Column % Row %
Age at diagnosis, years             
   30–39 4,903 5.0 49.5 885 4.5 8.9 569 11.6 5.7 3,558 11.1 35.9
   40–49 18,575 18.9 60.9 2,490 12.5 8.2 1,508 30.8 4.9 7,929 24.8 26.0
   50–59 21,807 22.1 61.4 4,464 22.5 12.5 1,161 23.7 3.3 8,094 25.4 22.8
   60–69 22,019 22.4 65.9 4,752 23.9 14.2 801 16.4 2.4 5,856 18.3 17.5
   70–79 20,667 21.0 68.2 4,662 23.4 15.4 584 11.9 1.9 4,401 13.8 14.5
   ≥80 10,492 10.6 67.7 2,633 13.2 17.0 273 5.6 1.8 2,092 6.6 13.5
Diagnosis year             
   1990–1992 16,500 16.8 61.6 3,751 18.9 14.0 1,111 22.7 4.1 5,435 17.0 20.3
   1993–1995 22,087 22.4 61.7 4,514 22.7 12.6 1,485 30.3 4.1 7,728 24.2 21.6
   1996–1998 27,734 28.2 64.2 5,239 26.3 12.1 1,367 27.9 3.2 8,884 27.8 20.5
   1999–2001 32,142 32.6 65.2 6,382 32.1 12.9 933 19.1 1.9 9,883 31.0 20.0
SEER registry             
   Atlanta, GA 5,696 5.8 59.4 1,171 5.9 12.2 381 7.8 4 2,344 7.3 24.4
   Connecticut 11,093 11.3 61.4 2,448 12.3 13.6 602 12.3 3.3 3,914 12.3 21.7
   Detroit, MI 10,559 10.7 60.4 2,314 11.6 13.2 539 11 3.1 4,063 12.7 23.3
   Hawaii 4,149 4.2 67.0 703 3.5 11.3 273 5.6 4.4 1,072 3.4 17.3
   Iowa 10,238 10.4 65.2 1,914 9.6 12.2 530 10.8 3.4 3,017 9.4 19.2
   Los Angeles, CA 15,586 15.8 61.4 3,399 17.1 13.4 919 18.8 3.6 5,491 17.2 21.6
   New Mexico 4,066 4.1 61.8 885 4.5 13.5 193 3.9 2.9 1,435 4.5 21.8
   San Francisco-Oakland, CA 13,063 13.3 63.9 2,750 13.8 13.5 652 13.3 3.2 3,957 12.4 19.4
   San Jose, CA 5,474 5.5 65.3 1,134 5.7 13.5 228 4.7 2.7 1,548 4.9 18.5
   Seattle, WA 14,241 14.5 68 2,517 12.7 12.0 423 8.6 2.0 3,770 11.8 18.0
   Utah 4,298 4.4 66.9 651 3.3 10.1 156 3.2 2.5 1,319 4.1 20.5
Race             
   Non-Hispanic white 78,805 81.7 65.4 15,716 80.5 13.0 3,515 73.5 2.9 22,532 72.1 18.7
   African-American 5,724 5.9 48.0 1,488 7.6 12.5 504 10.5 4.2 4,206 13.5 35.3
   Native American 284 0.3 55.0 57 0.3 11.0 23 0.5 4.5 152 0.5 29.5
   Asian/Pacific Islander 6,065 6.3 65.1 1,061 5.4 11.4 382 8.0 4.1 1,805 5.8 19.4
   Hispanic white 5,585 5.8 57.8 1,203 6.2 12.4 359 7.5 3.7 2,524 8.1 26.1
   Other/Unknown 2,000 - - 361 - - 113 - - 711 - -
Tumor histology             
   Ductal 71,199 72.3 62.7 13,981 70.3 12.3 3,641 74.4 3.2 24,722 77.4 21.8
   Lobular 8,980 9.1 73.6 2,160 10.9 17.7 283 5.8 2.3 784 2.5 6.4
   Ductal/Lobular 7,576 7.7 76.7 1,341 6.7 13.6 233 4.8 2.4 722 2.3 7.3
   Inflammatory 543 0.5 37.8 191 1.0 13.3 90 1.8 6.3 611 1.9 42.6
   Mucinous 2,927 3.0 80.9 486 2.4 13.5 41 0.8 1.1 164 0.5 4.5
   Tubular 1,696 1.7 79 327 1.6 15.2 44 0.9 2.1 79 0.3 3.7
   Comedo 1,159 1.2 43.6 318 1.6 12.0 179 3.6 6.7 1,003 3.1 37.7
   Medullary 266 0.3 14.7 148 0.8 8.2 97 2.0 5.4 1,292 4.0 71.7
   Papillary 582 0.6 79.0 58 0.3 7.9 10 0.2 1.3 87 0.3 11.8
   Other 3,535 3.6 49.4 876 4.4 12.2 278 5.7 3.9 2,466 7.7 34.5
Tumor stage             
   I 50,172 52.4 69.2 9,232 48 12.7 1,999 42.7 2.8 11,114 36.2 15.3
   II 37,335 39.0 60.3 7,606 39.5 12.3 2,068 44.2 3.3 14,878 48.4 24.1
   III 5,332 5.5 51.3 1,471 7.6 14.1 385 8.2 3.7 3,210 10.4 30.9
   IV 2,943 3.1 52.1 936 4.9 16.6 230 4.9 4.1 1,536 5.0 27.2
   Unstaged 2,681 - - 641 - - 214 - - 1,192 - -
Tumor grade             
   1 18,012 21.8 81.1 2,885 17.5 13.0 405 9.9 1.8 914 3.3 4.1
   2 40,642 49.3 74.2 7,133 43.4 13.0 1,324 32.5 2.4 5,682 20.6 10.4
   3 22,082 26.8 44.4 6,027 36.6 12.1 2,174 53.3 4.4 19,412 70.4 39.1
   4 1,774 2.1 45.0 413 2.5 10.5 173 4.3 4.4 1,579 5.7 40.1
   Unknown 15,953 -   3,428 -   820 -   4,343 -  
Tumor size (cm)             
   0–1.9 56,547 59.9 69.2 10,302 54.6 12.6 2,271 49.5 2.8 12,576 41.8 15.4
   2–5 32,977 34.9 58.7 7,135 37.8 12.7 1,891 41.3 3.4 14,147 47.1 25.2
   >5 4,949 5.2 48.8 1,432 7.6 14.1 422 9.2 4.2 3,330 11.1 32.9
   Unknown 3,990 - - 1,017 - - 312 - - 1,877 - -
Axillary lymph node status             
   Negative 54,948 65.3 64.8 10,428 63.0 12.3 2,622 61.0 3.1 16,749 60.3 19.8
   Positive 29,234 34.7 60.9 6,110 37.0 12.7 1,675 39.0 3.5 11,015 39.7 22.9
   Unknown 14,281 - - 3,348 - - 599 - - 4,166 - -
Surgical treatment             
   Performed 96,387 98.0 63.7 19,216 96.7 12.7 4,764 97.4 3.2 30,847 96.8 20.4
   Not performed 2,012 2.0 52.7 648 3.3 17.0 126 2.6 3.3 1,032 3.2 27
   Unknown 64 - - 22 - - 6 - - 51 - -
Radiation therapy             
   Treated 46,859 48.5 65.5 8,694 44.5 12.1 2,048 42.9 2.9 13,922 44.8 19.5
   None 49,776 51.5 61.9 10,836 55.5 13.4 2,725 57.1 3.4 17,131 55.2 21.3
   Unknown 1,828 - - 356 - - 123 - - 877 - -
  1. ER, estrogen receptor; PR, progesterone receptor; SEER, Surveillance, Epidemiology, and End Results.