|
Haplotype
|
Cases (percentage)
|
Controls (percentage)
|
OR (95% CI)a
|
|---|
|
z1 G-G-T-T-A
|
1,250 (49.4)
|
1,691 (48.2)
|
1.00 (reference)
|
|
z2 G-G-T-C-A
|
435 (17.2)
|
667 (19.0)
|
0.84 (0.72–0.98)
|
|
z3 G-C-T-T-A
|
403 (15.9)
|
544 (15.5)
|
0.99 (0.85–1.17)
|
|
z4 C-G-G-C-A
|
358 (14.1)
|
507 (14.5)
|
0.92 (0.79–1.09)
|
|
z5 C-G-G-C-G
|
53 (2.1)
|
63 (1.8)
|
1.16 (0.78–1.72)
|
| | | |
Global p = 0.15
|
-
aUnconditional logistic regression controlled for age, BMI at age 18 years, menopausal status at diagnosis, history of benign breast disease, and family history of breast cancer. CI, confidence interval; OR, odds ratio; PTGS2, prostaglandin endoperoxide synthase 2.
