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Table 1 Summary characteristics for affected and unaffected carriers

From: Parity and breast cancer risk among BRCA1 and BRCA2mutation carriers

Parameter

Total

Affected

Unaffected

  

BRCA1

BRCA2

BRCA1

BRCA2

Number of carriers, n

789

248

209

218

114

Age at censoring, years (mean ± SD)

45.0 ± 11.3

42.9 ± 9.6

43.9 ± 9.3

46.8 ± 13.0

48.3 ± 13.0

Year of birth, n (%)

     

   Before 1940

247

78 (31.5)

64 (30.6)

78 (35.8)

27 (23.7)

   1940 to 1949

185

69 (27.8)

61 (29.2)

40 (18.3)

15 (13.2)

   1950 to 1959

169

58 (23.4)

48 (23.0)

34 (15.6)

29 (25.4)

   1960 and after

188

43 (17.3)

36 (17.2)

66 (30.3)

43 (37.7)

Censoring age, n (%)

     

   <55 years

670

226 (91.1)

185 (88.5)

172 (78.9)

87 (76.3)

   ≥55 years

119

22 (8.9)

24 (11.5)

46 (21.1)

27 (23.7)

Oophorectomy before censoring age, n

45

5

7

25

8