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Table 4 List of 43 genes able to discriminate between well- and poorly differentiated DCIS

From: Classification of ductal carcinoma in situ by gene expression profiling

Rank NKI ID Symbol Annotation Accession no.
1 108691 ACK1 Activated p21cdc42Hs kinase AA427891
2 109246 BCL2 B-cell CLL/lymphoma 2 W63749
3 109268 ALDH3A2 Aldehyde dehydrogenase 3 family, member A2 AA633569
4 109236 BTD Biotinidase R17765
5 108595 CCL19 Small inducible cytokine subfamily A (Cys-Cys), member 19 AA680186
6 100524 CELSR2 Cadherin, EGF LAG seven-pass G-type receptor 2, flamingo (Drosophila) homolog H39187
7 126868 TMC4 DKFZP586J0619 protein AA991211
8 100708 SLC39A6 LIV-1 protein, oestrogen regulated H29315
9 109170 C4A Complement component 4A AA664406
10 109127 ESR1 Oestrogen receptor 1 AA291749
11 128702   EST AI313031
12 121012 HSHIN1 Hin-1 AA902831
13 128095 PCSK6 Paired basic amino acid cleaving system 4 W85807
14 128052 ARHGEF7 PAK-interacting exchange factor beta AA452871
15 128493 GMFG Glia maturation factor, gamma AI311932
16 123382 HIG1 Likely ortholog of mouse hypoxia induced gene 1 T74105
17 129689 C1orf21 Chromosome 1 open reading frame 21 AA406569
18 102289 ETFA Electron-transfer-flavoprotein, alpha polypeptide (glutaric aciduria II) T57919
19 126124 FLJ20152 Hypothetical protein AA918685
20 127815 PLAT Plasminogen activator, tissue R38933
21 101559 NPY1R Neuropeptide Y receptor Y1 R43817
22 100260 MAL Mal, T-cell differentiation protein AA227885
23 127969 CRYAA Crystallin, alpha A H84722
24 128244 SERPINA3 Serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 AA704242
25 108649   Human clone 23948 mRNA sequence H15114
26 106399 GRTP1 Hypothetical protein FLJ22474 N52651
27 123478 FLJ14712 Hypothetical protein FLJ14712 N79050
28 117207 EMP3 Epithelial membrane protein 3 W73810
29 111787 ZNF451 H. sapiens cDNA FLJ13010 fis, clone NT2RP3000542 AA486412
30 109502 KITLG H. sapiens cDNA: FLJ21592 fis, clone COL07036 H11088
31 109315 UCP2 Uncoupling protein 2 (mitochondrial, proton carrier) H61243
32 118532 NUPL1 PRO2463 protein AA772502
33 100263 MYB V-myb avian myeloblastosis viral oncogene homolog N49284
34 128249 CD3E CD3E antigen, epsilon polypeptide (TiT3 complex) AA933862
35 131226 IL7R Interleukin 7 receptor T65739
36 100104 SELL Selectin L (lymphocyte adhesion molecule 1) H00662
37 108671 BCAT2 Branched chain aminotransferase 2, mitochondrial AA436410
38 116984 ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide AA708298
39 108376 LAMA3 Laminin, alpha 3 (nicein [150 kD], kalinin [165 kD], BM600 [150 kD], epilegrin) AA001432
40 104944 SLC7A2 Solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 R26163
41 100840 THOC1 Nuclear matrix protein p84 AA129297
42 100650 SHFM1 Deleted in split-hand/split-foot 1 region H85464
43 101429 SIAT1 Sialyltransferase 1 (beta-galactoside alpha-2,6-sialytransferase) AA598652
  1. DCIS, ductal carcinoma in situ; EST, expressed sequence tag; NKI ID, Netherlands Cancer Institute (Amsterdam, The Netherlands) identification number.
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