Table 3 List of 80 genes able to discriminate between poorly differentiated DCIS and invasive grade 3 breast tumours

1

123776

PIAS4

Protein inhibitor of activated STAT protein

H30547

2

129658

MGC13045

DnaJ (Hsp40) homolog, subfamily C, member 4

AA996059

3

121937

FLJ10374

Hypothetical protein FLJ10374

AA676962

4

102847

YIF1

Putative transmembrane protein; homolog of yeast Golgi membrane protein Yif1p (Yip1p-interacting factor)

H79351

5

127755

TGFB2

Transforming growth factor, beta 2

W47556

6

117289

MMP11

Matrix metalloproteinase 11 (stromelysin 3)

AA045500

7

104973

SYNPO2

Synaptopodin 2

R31679

8

121066

DAPK3

Death-associated protein kinase 3

AA973730

9

128493

GMFG

Glia maturation factor, gamma

AI311932

10

105533

ARF1

ADP-ribosylation factor 1

W45572

11

132031

NY-REN-24 antigen

AA918005

12

127881

NFIC

Nuclear factor I/C (CCAAT-binding transcription factor)

T59427

13

120649

KCTD5

Potassium channel tetramerisation domain containing 5

AA521027

14

120934

EIF4G1

Eukaryotic translation initiation factor 4 gamma, 1

R37276

15

105453

PSAP

Prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy)

N72215

16

112695

SYNPO2

H. sapiens cDNA FLJ20767 fis, clone COL06986

AA043349

17

101577

BMI1

Murine leukaemia viral (bmi-1) oncogene homolog

AA478036

18

105479

BAT3

HLA-B-associated transcript-3

AA434416

19

123071

C9orf82

Hypothetical protein FLJ13657

AA135972

20

101638

ID4

Inhibitor of DNA binding 4, dominant negative helix-loop-helix protein

AA464856

21

115306

LRP16

LRP16 protein

AA456318

22

118143

STX1B2

ESTs, moderately similar to ST1B_HUMAN SYNTAXIN 1B [H. sapiens]

H41572

23

128106

DUSP6

Dual specificity phosphatase 6

AA455254

24

115676

RPS15A

Ribosomal protein S15a

AA411682

25

108595

CCL19

Small inducible cytokine subfamily A (Cys-Cys), member 19

AA680186

26

126589

C6orf166

Hypothetical protein FLJ10342

AA984953

27

131540

PRPF31

DKFZP566J153 protein

AI253017

28

109065

SYT5

H39018

29

128198

MMP11

Matrix metalloproteinase 11 (stromelysin 3)

AA954935

30

109364

MYST2

Histone acetyltransferase

H11938

31

106989

TNFSF13

Tumour necrosis factor (ligand) superfamily, member 13

AA443577

32

109798

T82459

33

131890

CDH1

Cadherin 1, type 1, E-cadherin (epithelial)

AI671174

34

111513

COG3

H. sapiens clone 25226 mRNA sequence

AA461166

35

108645

HMGCS2

3-Hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial)

AA496149

36

101651

TRAP1

Heat shock protein 75

AA497020

37

105304

LRP16

LRP16 protein

W52182 | AA284285

38

105363

ARL7

ADP-ribosylation factor-like 7

AA485683

39

127890

PTMS

Parathymosin

AA458981

40

118682

NBS1

Nijmegen breakage syndrome 1 (nibrin)

H98655

41

108997

PTTG1IP

Pituitary tumour-transforming 1 interacting protein

AA156461

42

110281

HSPA1L

Heat shock 70-kD protein-like 1

H17513

43

125700

APC2

Adenomatous polyposis coli like

AA976241

44

117139

ALDOB

Aldolase B, fructose-bisphosphate

H72098

45

107595

SOX17

SRY-box 17

AA427400 | AI732705

46

107375

NUCKS

Similar to rat nuclear ubiquitous casein kinase 2

AA137266

47

109238

BSG

Basigin (OK blood group)

AA436440

48

122821

NSE2

ESTs

H30453

49

123689

LOC339123

STIP1 homology and U-Box containing protein 1

R54844

50

115953

LOC146542

Human Chromosome 16 BAC clone CIT987SK-A-635H12

AA455010

51

108960

GABRD

H41122

52

128222

GLUL

Glutamate-ammonia ligase (glutamine synthase)

AI000103

53

100222

NFIX

Nuclear factor I/X (CCAAT-binding transcription factor)

AA406269

54

105470

ISYNA1

Myo-inositol 1-phosphate synthase A1

AA454554

55

117998

RBM9

RNA binding motif protein 9

H03903

56

105404

GDF15

Prostate differentiation factor

N26311

57

127811

TOB1

Transducer of ERBB2, 1

W96163

58

105524

RPS6KA4

Ribosomal protein S6 kinase, 90-kD, polypeptide 4

AA443601

59

109232

BCKDHA

Branched chain keto acid dehydrogenase E1, alpha polypeptide (maple syrup urine disease)

AA477298

60

115741

APPL

Adaptor protein containing pH domain, PTB domain and leucine zipper motif

AA436158

61

100898

ELF3

E74-like factor 3 (ets domain transcription factor, epithelial-specific)

AA434373

62

101067

MAP7

Microtubule-associated protein 7

R77252 | R77251

63

109306

AQP1

Aquaporin 1 (channel-forming integral protein, 28 kD)

H24316

64

102326

CYC1

Cytochrome c-1

AA447774

65

108988

MALAT1

Histone deacetylase 3

H88540

66

102253

ACTG2

Actin, gamma 2, smooth muscle, enteric

T60048

67

116834

GPC1

Glypican 1

AA455896

68

105497

HNRPK

Heterogeneous nuclear ribonucleoprotein K

W85697

69

108372

LCP1

Lymphocyte cytosolic protein 1 (L-plastin)

W73144

70

128634

PRCP

Prolylcarboxypeptidase (angiotensinase C)

AI360366

71

106297

PHF17

Hypothetical protein FLJ22479

AA136664

72

101616

KRT19

Keratin 19

AA464250

73

128532

LTB

Lymphotoxin beta (TNF superfamily, member 3)

AI351740

74

102385

F13A1

Coagulation factor XIII, A1 polypeptide

AA449742

75

102673

WHSC1L1

Wolf-Hirschhorn syndrome candidate 1-like 1

T97900

76

109638

CXXC1

CpG binding protein

T60082

77

109116

FBL

Fibrillarin

AA663986

78

109425

TUBB

Tubulin, beta polypeptide

AA427899

79

117500

EST

AA621138

80

100656

UBE2C

Ubiquitin carrier protein E2-C

AA430504