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Table 1 Progenitor cell properties (CD44+/CD24-) of various breast cancer cell lines

From: CD44+/CD24-breast cancer cells exhibit enhanced invasive properties: an early step necessary for metastasis

Cell line CD44+/CD24- CD44+/CD24+ CD44-/CD24+ CD44-/CD24- Tumor typea [24,50-52] Tissue sourceb [24,50-52] Cell type classification [25-27]
MDA-MB-231, TMD-231 85 ± 5 2 0 13 ± 5 AC Pleural effusion Mesenchymal
TMD-436 72 ± 5 27 ± 5 0 7 AC Pleural effusion Myoepithelial
Hs578T 86 ± 5 10 ± 5 0 2 ± 2 CS Primary Mesenchymal
SUM1315 97 ± 3 0 0 3 ± 3 IDAC Metastatic nodule Basal
HBL-100 37 ± 5 8 2 52 ± 6 Immortal Milk Myoepithelial
MDA-MB-468 3 ± 1 90 ± 6 7 ± 3 0 IAC Pleural effusion Basal
MCF-7 0 8 ± 3 87 ± 2 6 ± 2 IDAC Pleural effusion Luminal
T47-D 0 0 63 ± 3 37 ± 2 IDAC Pleural effusion Luminal
ZR-75-1 0 0 64 ± 1 36 ± 1 IDAC Ascites Luminal
BT-474 0 0 78 ± 7 22 ± 7 IDC Primary Luminal/ErbB2+
SK-BR-3 0 0 84 ± 1 16 ± 1 AC Pleural effusion Luminal/ErbB2+
DU4475 0 0 6 ± 1 94 ± 1 IDC Cutaneous nodule ND
MCF-10Aa 17 ± 4 5 ± 3 20 ± 10 58 ± 20 Immortal Fibrocyst Basal
  1. aPercentage of MCF10A cell progenitor and other subpopulation was influenced by species and batch of serum in culture media. AC, adenocarcinoma; CS, carcinosarcoma; IDAC, infiltrating ductal adenocarcinoma; IAC, Invasive adenocarcinoma; IDC, Invasive ductal carcinoma; ND, not determined.