Table 1 Progenitor cell properties (CD44+/CD24-) of various breast cancer cell lines
Cell line | CD44+/CD24- | CD44+/CD24+ | CD44-/CD24+ | CD44-/CD24- | Tumor typea [24,50-52] | Tissue sourceb [24,50-52] | Cell type classification [25-27] |
|---|---|---|---|---|---|---|---|
MDA-MB-231, TMD-231 | 85 ± 5 | 2 | 0 | 13 ± 5 | AC | Pleural effusion | Mesenchymal |
TMD-436 | 72 ± 5 | 27 ± 5 | 0 | 7 | AC | Pleural effusion | Myoepithelial |
Hs578T | 86 ± 5 | 10 ± 5 | 0 | 2 ± 2 | CS | Primary | Mesenchymal |
SUM1315 | 97 ± 3 | 0 | 0 | 3 ± 3 | IDAC | Metastatic nodule | Basal |
HBL-100 | 37 ± 5 | 8 | 2 | 52 ± 6 | Immortal | Milk | Myoepithelial |
MDA-MB-468 | 3 ± 1 | 90 ± 6 | 7 ± 3 | 0 | IAC | Pleural effusion | Basal |
MCF-7 | 0 | 8 ± 3 | 87 ± 2 | 6 ± 2 | IDAC | Pleural effusion | Luminal |
T47-D | 0 | 0 | 63 ± 3 | 37 ± 2 | IDAC | Pleural effusion | Luminal |
ZR-75-1 | 0 | 0 | 64 ± 1 | 36 ± 1 | IDAC | Ascites | Luminal |
BT-474 | 0 | 0 | 78 ± 7 | 22 ± 7 | IDC | Primary | Luminal/ErbB2+ |
SK-BR-3 | 0 | 0 | 84 ± 1 | 16 ± 1 | AC | Pleural effusion | Luminal/ErbB2+ |
DU4475 | 0 | 0 | 6 ± 1 | 94 ± 1 | IDC | Cutaneous nodule | ND |
MCF-10Aa | 17 ± 4 | 5 ± 3 | 20 ± 10 | 58 ± 20 | Immortal | Fibrocyst | Basal |