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Table 6 Estimated number of deaths up to the end of the year 2002 in the Million Women Study cohort and minimum and maximum detectable relative risks for certain common conditions

From: The Million Women Study: design and characteristics of the study population

   Current versus never users Current users of 5+ years duration versus never users
Cause of death Expected number of deaths* Minimum detectable RR > 1 Maximum detectable RR < 1 Minimum detectable RR > 1 Maximum detectable RR < 1
All cancers 12 600 1.06 0.94 1.08 0.92
   Colorectal cancer 1200 1.20 0.82 1.25 0.77
   Lung cancer 2000 1.15 0.86 1.19 0.82
   Breast cancer 2800 1.13 0.88 1.16 0.85
   Ovarian cancer 1100 1.20 0.81 1.26 0.76
   Endometrial cancer 250 1.41 0.65 1.53 0.56
All circulatory disease 8000 1.08 0.93 1.10 0.91
   Ischaemic heart disease 5000 1.09 0.91 1.12 0.88
   Stroke 1700 1.16 0.85 1.21 0.81
All causes of death 23 200 1.05 0.95 1.06 0.94
  1. *Based on national mortality rates for 1996 in England and Wales with the assumption that death rates from causes other than breast cancer are 20% lower than the national rate and that breast cancer death rates are 30% lower than the national rate. Detectable at the 95% significance level with 80% power, assuming that death rates among never users are equivalent to national rates. RR, risk ratio.