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Table 1 Clinicopathological characteristics and gene expression variation of each patient

From: Comparison of gene expression profiles in core biopsies and corresponding surgical breast cancer samples

         Difference in gene expression between CB and ST (ΔCt [GeneST] – ΔCt [GeneCB])
Patient number Age Time between CB and ST (days) Histology Tumor diameter (cm) Grade Lymph node involvement Correlation (rs) between paired CB and ST PAI-1 COX-2 ERBB2
1 68 7 Ductal 3.3 3 Negative 0.97 -0.39 -0.15 -0.08
2 59 8 Ductal 1.8 3 Negative 0.98 -1.68 -0.20 0.52
3 49 21 Ductal 3.3 2 Positive 0.98 -1.19 -1.03 0.62
4 57 13 Ductal 1.1 1 Positive 0.89 -0.63 0.61 -0.02
5 63 14 Ductal 9.0 2 Negative 0.97 -1.41 -1.80 1.40
6 60 21 Ductulo-lobular 2.7 1 Positive 0.98 -1.38 -2.41 0.23
7 80 12 Ductal 3.1 1 Positive 0.95 -2.62 -1.39 0.44
8 81 14 Lobular 2.8 2 Positive 0.94 -3.78 -3.73 0.29
9 34 14 Ductal 1.8 2 Negative 0.95 -3.16 -1.37 0.12
10 68 10 Ductal 0.9 2 Micrometastasis 0.87 -3.57 -7.27 1.01
11 65 16 Lobular 1.9 1 Negative 0.89 -5.16 -0.80 -0.02
12 80 13 Ductal 6.0 3 Positive 0.86 -2.16 -0.20 0.63
13 59 2 Apocrine 2.7 3 Negative 0.98 -1.18 -4.64 -0.27
14 73 12 Lobular 1.9 2 Positive 0.95 -4.60 -3.97 -1.85
15 61 1 Lobular 2.3 2 Positive 0.89 -1.88 -1.61 -0.94
16 73 22 Ductal 1.9 2 Negative 0.98 -1.28 -0.34 0.26
17 58 3 Ductal 9.0 2 Positive 0.96 -0.48 0.26 -0.42
19 68 13 Ductal 1.2 1 Negative 0.97 -2.18 -2.62 0.31
18a 67 11 Ductal 1.5 2 Micrometastasis NA NA NA NA
20 44 13 Ductulo-lobular 3.2 3 Positive 0.98 -0.12 0.01 0.19
21 71 20 Ductulo-lobular 1.7 3 Negative 0.95 -3.15 -1.69 0.26
22 53 5 Ductal 1.3 2 Negative 0.92 -2.81 -5.48 -0.08
  1. aRNA in the core biopsy (CB) of this patient was degraded and, therefore, omitted from the study. COX, cyclooxygenase; NA, not available; PAI-1, Plasminogen Activator Inhibitor-1; ST, surgical tumor tissue specimen.