| | | | | | | | |
Difference in gene expression between CB and ST (ΔCt [GeneST] – ΔCt [GeneCB])
|
|---|
|
Patient number
|
Age
|
Time between CB and ST (days)
|
Histology
|
Tumor diameter (cm)
|
Grade
|
Lymph node involvement
|
Correlation (rs) between paired CB and ST
|
PAI-1
|
COX-2
|
ERBB2
|
|---|
|
1
|
68
|
7
|
Ductal
|
3.3
|
3
|
Negative
|
0.97
|
-0.39
|
-0.15
|
-0.08
|
|
2
|
59
|
8
|
Ductal
|
1.8
|
3
|
Negative
|
0.98
|
-1.68
|
-0.20
|
0.52
|
|
3
|
49
|
21
|
Ductal
|
3.3
|
2
|
Positive
|
0.98
|
-1.19
|
-1.03
|
0.62
|
|
4
|
57
|
13
|
Ductal
|
1.1
|
1
|
Positive
|
0.89
|
-0.63
|
0.61
|
-0.02
|
|
5
|
63
|
14
|
Ductal
|
9.0
|
2
|
Negative
|
0.97
|
-1.41
|
-1.80
|
1.40
|
|
6
|
60
|
21
|
Ductulo-lobular
|
2.7
|
1
|
Positive
|
0.98
|
-1.38
|
-2.41
|
0.23
|
|
7
|
80
|
12
|
Ductal
|
3.1
|
1
|
Positive
|
0.95
|
-2.62
|
-1.39
|
0.44
|
|
8
|
81
|
14
|
Lobular
|
2.8
|
2
|
Positive
|
0.94
|
-3.78
|
-3.73
|
0.29
|
|
9
|
34
|
14
|
Ductal
|
1.8
|
2
|
Negative
|
0.95
|
-3.16
|
-1.37
|
0.12
|
|
10
|
68
|
10
|
Ductal
|
0.9
|
2
|
Micrometastasis
|
0.87
|
-3.57
|
-7.27
|
1.01
|
|
11
|
65
|
16
|
Lobular
|
1.9
|
1
|
Negative
|
0.89
|
-5.16
|
-0.80
|
-0.02
|
|
12
|
80
|
13
|
Ductal
|
6.0
|
3
|
Positive
|
0.86
|
-2.16
|
-0.20
|
0.63
|
|
13
|
59
|
2
|
Apocrine
|
2.7
|
3
|
Negative
|
0.98
|
-1.18
|
-4.64
|
-0.27
|
|
14
|
73
|
12
|
Lobular
|
1.9
|
2
|
Positive
|
0.95
|
-4.60
|
-3.97
|
-1.85
|
|
15
|
61
|
1
|
Lobular
|
2.3
|
2
|
Positive
|
0.89
|
-1.88
|
-1.61
|
-0.94
|
|
16
|
73
|
22
|
Ductal
|
1.9
|
2
|
Negative
|
0.98
|
-1.28
|
-0.34
|
0.26
|
|
17
|
58
|
3
|
Ductal
|
9.0
|
2
|
Positive
|
0.96
|
-0.48
|
0.26
|
-0.42
|
|
19
|
68
|
13
|
Ductal
|
1.2
|
1
|
Negative
|
0.97
|
-2.18
|
-2.62
|
0.31
|
|
18a
|
67
|
11
|
Ductal
|
1.5
|
2
|
Micrometastasis
|
NA
|
NA
|
NA
|
NA
|
|
20
|
44
|
13
|
Ductulo-lobular
|
3.2
|
3
|
Positive
|
0.98
|
-0.12
|
0.01
|
0.19
|
|
21
|
71
|
20
|
Ductulo-lobular
|
1.7
|
3
|
Negative
|
0.95
|
-3.15
|
-1.69
|
0.26
|
|
22
|
53
|
5
|
Ductal
|
1.3
|
2
|
Negative
|
0.92
|
-2.81
|
-5.48
|
-0.08
|
-
aRNA in the core biopsy (CB) of this patient was degraded and, therefore, omitted from the study. COX, cyclooxygenase; NA, not available; PAI-1, Plasminogen Activator Inhibitor-1; ST, surgical tumor tissue specimen.
