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Figure 5 | Breast Cancer Research

Figure 5

From: Estrogen receptor-α and progesterone receptor are expressed in label-retaining mammary epithelial cells that divide asymmetrically and retain their template DNA strands

Figure 5

Graphical depiction of percentage of LRECs that were either ER-α positive or PR positive after hormone treatments. All animals received [3H]thymidine at 5 weeks of age. Control animals (Con; white bar) received only [3H]thymidine. After a 7-week chase group I (GrpI; black bar) received estradiol injections; group II (GrpII; diagonal hatches) animals received estradiol and progesterone; and group III (GrpIII; vertical hatches) received estradiol, progesterone, and prolactin. (a) Results after 3-day hormone treatment and (b) results obtained after 5-day hormone treatment and 2-day recovery period. Error bars indicate the standard error of the mean. *P < 0.05, versus Con. ER, estrogen receptor; LREC, label-retaining epithelial cell; PR, progesterone receptor.

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