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Table 3 Correlation between immunohistochemical status of HER2, p53, and Ki67 and response to endocrine therapy

From: p53 protein accumulation predicts resistance to endocrine therapy and decreased post-relapse survival in metastatic breast cancer

  HER2 P53 Ki67
  Positive/total (percentage) P Positive/total (percentage) P Positive/total (percentage) P
Response to endocrine therapy (n = 73)
Total 9/73 (12.3)   16/73 (21.9)   26/73 (35.6)  
Responders 1/34 (2.9) 0.054 2/34 (5.9) 0.0049a 7/34 (20.6) 0.024a
Non-responders 8/39 (20.5)   14/39 (35.9)   19/39 (48.7)  
  1. a P < 0.05 is considered significant.