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Table 3 Correlation between immunohistochemical status of HER2, p53, and Ki67 and response to endocrine therapy

From: p53 protein accumulation predicts resistance to endocrine therapy and decreased post-relapse survival in metastatic breast cancer

 

HER2

P53

Ki67

 

Positive/total (percentage)

P

Positive/total (percentage)

P

Positive/total (percentage)

P

Response to endocrine therapy (n = 73)

Total

9/73 (12.3)

 

16/73 (21.9)

 

26/73 (35.6)

 

Responders

1/34 (2.9)

0.054

2/34 (5.9)

0.0049a

7/34 (20.6)

0.024a

Non-responders

8/39 (20.5)

 

14/39 (35.9)

 

19/39 (48.7)

 
  1. a P < 0.05 is considered significant.