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Table 2 Correlation between clinicopathological factors and molecular markers

From: p53 protein accumulation predicts resistance to endocrine therapy and decreased post-relapse survival in metastatic breast cancer

  HER2 P53 Ki67
  Positive/total (percentage) P Positive/total (percentage) P Positive/total (percentage) P
Total 9/73 (12.3)   16/73 (21.9)   26/73 (35.6)  
Tumour size (cm)
   <2.0 4/20 (20.0) 0.41 5/20 (25.0) 0.94 7/20 (35.0) >0.99
   ≥2.0 5/53 (9.4)   11/53 (20.8)   19/53 (35.8)  
Number of positive lymph nodes
   0 1/22 (4.5) 0.34 3/22 (12.6) 0.41 6/22 (27.2) 0.47
   ≥1 8/51 (15.7)   13/51 (25.5)   20/51 (39.2)  
Histological grade
   1 0/12 (0) 0.36 0/12 (0) 0.05 3/12 (25.0) 0.18
   2 6/42 (14.3)   9/42 (21.4)   13/42 (31.0)  
   3 3/19 (15.8)   7/19 (36.8)   10/19 (52.6)  
Estrogen receptor-α
Negative 4/17 (23.5) 0.23 5/17 (29.4) 0.60 8/17 (47.1) 0.40
Positive 5/56 (8.9)   11/56 (19.6)   18/56 (32.1)  
Progesterone receptor
Negative 3/18 (16.7) 0.81 5/18 (27.8) 0.71 9/18 (50.0) 0.23
Positive 6/55 (10.9)   11/55 (20.0)   17/55 (30.9)