Table 2 Correlation between clinicopathological factors and molecular markers
| Â | HER2 | P53 | Ki67 | |||
|---|---|---|---|---|---|---|
| Â | Positive/total (percentage) | P | Positive/total (percentage) | P | Positive/total (percentage) | P |
Total | 9/73 (12.3) | Â | 16/73 (21.9) | Â | 26/73 (35.6) | Â |
Tumour size (cm) | ||||||
   <2.0 | 4/20 (20.0) | 0.41 | 5/20 (25.0) | 0.94 | 7/20 (35.0) | >0.99 |
   ≥2.0 | 5/53 (9.4) |  | 11/53 (20.8) |  | 19/53 (35.8) |  |
Number of positive lymph nodes | ||||||
   0 | 1/22 (4.5) | 0.34 | 3/22 (12.6) | 0.41 | 6/22 (27.2) | 0.47 |
   ≥1 | 8/51 (15.7) |  | 13/51 (25.5) |  | 20/51 (39.2) |  |
Histological grade | ||||||
   1 | 0/12 (0) | 0.36 | 0/12 (0) | 0.05 | 3/12 (25.0) | 0.18 |
   2 | 6/42 (14.3) |  | 9/42 (21.4) |  | 13/42 (31.0) |  |
   3 | 3/19 (15.8) |  | 7/19 (36.8) |  | 10/19 (52.6) |  |
Estrogen receptor-α | ||||||
Negative | 4/17 (23.5) | 0.23 | 5/17 (29.4) | 0.60 | 8/17 (47.1) | 0.40 |
Positive | 5/56 (8.9) | Â | 11/56 (19.6) | Â | 18/56 (32.1) | Â |
Progesterone receptor | ||||||
Negative | 3/18 (16.7) | 0.81 | 5/18 (27.8) | 0.71 | 9/18 (50.0) | 0.23 |
Positive | 6/55 (10.9) | Â | 11/55 (20.0) | Â | 17/55 (30.9) | Â |