|
Genotype
|
Cases
|
Deaths
|
Hazard ratio minimally adjusteda (95% confidence interval)
|
Hazard ratio fully adjustedb (95% confidence interval)
|
|---|
|
Overall survival
|
230
|
75
|
P for trend = 0.46
|
P for trend = 0.42
|
|
CC
|
140
|
49
|
1 (reference)
|
1 (reference)
|
|
CT
|
73
|
21
|
0.83 (0.49–1.38)
|
0.67 (0.38–1.17)
|
|
TT
|
17
|
5
|
0.81 (0.32–2.04)
|
1.07 (0.42–2.74)
|
|
CC
|
140
|
49
|
1 (reference)
|
1 (reference)
|
|
CT + TT
|
90
|
26
|
0.82 (0.51–1.33)
|
0.73 (0.44–1.22)
|
|
Recurrence-free survival
|
220
|
85
|
P for trend = 0.16
|
P for trend = 0.12
|
|
CC
|
136
|
57
|
1 (reference)
|
1 (reference)
|
|
CT
|
68
|
24
|
0.79 (0.49–1.28)
|
0.64 (0.38–1.07)
|
|
TT
|
16
|
4
|
0.55 (0.20–1.52)
|
0.73 (0.26–2.049)
|
|
CC
|
136
|
57
|
1 (reference)
|
1 (reference)
|
|
CT + TT
|
84
|
28
|
0.75 (0.47–1.18)
|
0.65 (0.40–1.05)
|
- CC, homozygous for the wild-type manganese superoxide dismutase gene; CT, heterozygous for the variant genotype; TT, homozygous for the variant genotype. aMinimally adjusted model: age. bFully adjusted model: age, stage with node status at diagnosis, race, estrogen receptor status, and progesterone receptor status.
