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Table 3 Effects of combined alleles encoding reduced detoxification on radiation-related toxicities

From: Genetic predictors of acute toxicities related to radiation therapy following lumpectomy for breast cancer: a case-series study

Number of alleles

Patients

Toxicities

HRa (95% CI)

0 or 1

149

22

1.0

2

148

33

1.19 (0.61–2.382)

3 or 4

102

17

1.26 (0.72–2.21)

  1. P trend = 0.67. CI, confidence interval; HR, hazard ratio.