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Table 1 Patient characteristics and skin toxicity (>2c) among women receiving radiation therapy following breast conserving surgery

From: Genetic predictors of acute toxicities related to radiation therapy following lumpectomy for breast cancer: a case-series study

Characteristics

Patients (n)

Toxicities (n)

HRa (95% CI)

Age (years)

   

   ≤50

62

11

1.0

   >50 to 60

168

36

1.29 (0.65–2.57)

   >60 to 70

152

23

0.84 (0.41–1.76)

   >70

65

8

0.78 (0.31–1.97)

BMI (kg/m2)

   

   ≤25

229

23

1.0

   26–30

150

36

2.50 (1.45–4.30)

   >30

68

19

3.30 (1.76–6.21)

Skin sensitivity

   

   Always sunburn

113

17

1.0

   Sometimes sunburn

243

43

1.15 (0.65–2.04)

   Never sunburn

80

16

1.49 (0.74–2.99)

Current smoking

   

   No

399

67

1.0

   Yes

48

11

1.54 (0.79–3.01)

Alcohol consumption

   

   No

110

12

1.0

   Yes

321

61

1.88 (1.00–3.53)

Radiotherapy of lymph nodes

   

   No

397

67

1.0

   Yes

50

11

1.32 (0.66–2.63)

Hormone therapy

   

   No

68

9

1.0

   Yes

379

69

1.51 (0.75–3.04)

  1. aHazard ratio adjusted for clinic, photon field, beam energy, and boost method; numbers vary because of missing data. BMI, body mass index; CI, confidence interval; HR, hazard ratio.