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Table 4 Incidence of central nervous system relapses as the only manifestation of disease progression in breast cancer patients according to the detection of cytokeratin 19 mRNA-positive cells in peripheral blood

From: Central nervous system relapse in patients with breast cancer is associated with advanced stages, with the presence of circulating occult tumor cells and with the HER2/neu status

Cytokeratin 19 mRNA cells CNS relapses (n = 40) P value
  n Percentage  
Positive (n = 78) 26 33.3 0.004
Negative (n = 414) 14 3.4