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Table 3 Incidence of central nervous system metastasis as the only manifestation of disease progression according to the stage of disease

From: Central nervous system relapse in patients with breast cancer is associated with advanced stages, with the presence of circulating occult tumor cells and with the HER2/neu status

 

CNS relapses (n = 40)

P value

 

Group A (n = 32)

Group B (n = 8)

 

Stage I/stage II

6 (15%)

3 (7.5%)

0.367

Stage IIIb/stage IV

26 (65%)

5 (12.5%)

0.143

All stages

32 (80%)

8 (20%)

0.048

  1. Group A, patients with breast cancer treated with a taxane-containing regimen; group B, patients with breast cancer treated with a nontaxane-containing regimen.