Figure 2
From: Keratin 6 is not essential for mammary gland development
Keratin 6a (K6a) expression during mammary gland development. Tissues isolated from C57Bl/6 mice during various stages of mammary gland development were stained by immunohistochemistry with an antibody to detect K6a expression. (a) Embryonic day 14 mammary bud, (b) embryonic day 16.5 mammary bud, (c) day 5 pup, (d,e) 6-week terminal end bud, (f) 6-week pubertal duct, (g) 12-week mature duct treated for 2 days with estrogen and progesterone, (h) mature duct after treatment for 21 days with estrogen and progesterone, (i) day 10 pregnancy, (j) day 15 pregnancy, (k) day 18 pregnancy, (l) lactation day 2, (m) lactation day 9, (n) involution day 3, (o) 12-week mature duct from CCAAT-enhancer-binding protein-β-null mammary gland, (p) 12-week mature duct from K6ab-null mammary gland. Scale bar, 100 μm.