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Table 1 Selected characteristics of the study population

From: A population-based study of tumor gene expression and risk of breast cancer death among lymph node-negative patients

Characteristic

Cases (n = 220)

Controls (n = 570)

Matched variables

    

Age at diagnosis (years)

    

   <40

17

(8%)

23

(4%)

   40–49

42

(19%)

127

(22%)

   50–59

64

(29%)

152

(27%)

   60–74

97

(44%)

268

(47%)

Race/ethnicity

    

   White, non-Hispanic

172

(78%)

457

(80%)

   White, Hispanic

7

(3%)

13

(2%)

   Black

20

(9%)

47

(8%)

   Asian

21

(10%)

53

(9%)

Surgery year

    

   1985–1989

146

(66%)

385

(68%)

   1990–1994

74

(34%)

185

(32%)

Adjuvant tamoxifen

    

   No

156

(71%)

393

(69%)

   Yes

64

(29%)

177

(31%)

Unmatched variables

    

ER status from RT-PCR1

    

   Positive

168

(76%)

514

(90%)

   Negative

52

(24%)

56

(10%)

Tumor size (cm)

    

   ≤1

49

(22%)

193

(34%)

   1.1–2

93

(42%)

255

(45%)

   2.1–4

72

(33%)

114

(20%)

   >4

6

(3%)

8

(1%)

Tumor grade (differentiation)2

    

   Well

25

(11%)

175

(31%)

   Moderate

92

(42%)

261

(46%)

   Poor

103

(47%)

134

(23%)

Recurrence Score

    

   Low risk (<18)

57

(26%)

322

(56%)

   Intermediate risk (18–30)

54

(25%)

108

(19%)

   High risk (≥31)

109

(50%)

140

(25%)

  1. 1Cutoff points based on RT-PCR values: ≤6.5 and >6.5 units. 2Bloom-Richardson grading criteria, pathologist 1. ER, estrogen receptor; RT-PCR, reverse transcription polymerase chain reaction.
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Breast Cancer Research

ISSN: 1465-542X

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