Classification and risk stratification of invasive breast carcinomas using a real-time quantitative RT-PCR assay

Breast Cancer Research

Table 1 Correlating proliferation genes with relapse-free survival (RFS) and the grade using the quantitative reverse-transcription PCR assay

Gene	RFS-gene					Grade-gene
	All samples	Luminal only	All samples adjusted for grade	All samples adjusted for stage	All samples adjusted for stage and grade	Spearman correlation	P value
BIRC5	0.136	0.0679	0.493	0.146	0.348	0.349	0.000156
BUB1	0.00247	0.0658	0.0178	0.00872	0.0258	0.45	6.84 × 10^-7
CENPF	0.0204	0.0173	0.149	0.0934	0.295	0.469	2.00 × 10^-7
CKS2	0.34	0.621	0.961	0.125	0.313	0.364	7.57 × 10^-5
DUFD1	0.0525	0.0411	0.261	0.188	0.417	0.406	8.93 × 10^-6
GTPBP4	0.000813	0.0751	0.00636	0.00177	0.00587	0.258	0.00598
HSPA14	0.0527	0.1	0.219	0.00491	0.0132	0.264	0.00467
MK167	0.101	0.0591	0.297	0.119	0.255	0.354	0.000121
MYBL2	0.00229	0.00246	0.0123	0.0318	0.0777	0.409	7.48 × 10^-6
NEK2	0.0654	0.436	0.259	0.155	0.346	0.384	2.89 × 10^-5
PCNA	0.155	0.166	0.179	0.182	0.152	0.151	0.109
STK6	0.000707	0.0485	0.00602	0.00816	0.0204	0.427	2.67 × 10^-6
TOP2A	0.0347	0.291	0.142	0.0871	0.198	0.325	0.000451
TTK	0.00688	0.0651	0.0571	0.0299	0.11	0.4	1.26 × 10^-5
Meta-gene	0.00321	0.0185	0.0252	0.0102	0.0301	0.456	4.77 × 10^-7

ISSN: 1465-542X