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Table 4 Cytoplasmic HER4: correlation with pathological variables and HER family

From: HER4 in breast cancer: comparison of antibodies against intra- and extra-cellular domains of HER4

 

Test

H4.77.16 histoscore

HFR1 histoscore

  

P value

Correlation

P value

Correlation

NPI

Kendall's tau-b

0.004

Positive

<0.001

Positive

Size

Kendall's tau-b

<0.001

Positive

0.021

Positive

Grade

Kendall's tau-b

0.076

 

<0.001

Positive

Nodal

Kendall's tau-b

0.004

Positive

<0.001

Positive

EGFR

Mann-Whitney

0.035

 

0.436

 

HER2

Mann-Whitney

0.381

 

0.771

 

HER3

Mann-Whitney

<0.001

Positive

0.001

Positive

  1. Grade is the Bloom and Richardson grade. Nodal status is the number of positive nodes. NPI, Nottingham Prognostic Index (grade + nodal status + 0.02 × size in mm). EGFR, epidermal growth factor receptor.