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Table 5 Haplotype specific odds ratios adjusted for age and association with tumor characteristics

From: Germline polymorphisms in SIPA1are associated with metastasis and other indicators of poor prognosis in breast cancer

Haplotypea

Positive nodes

ER status

PR status

 

OR (95% CI)

P

OR (95% CI)

P

OR (95% CI)

P

1

1.00

 

1.00

 

1.00

 

2

1.14 (0.52–2.51)

0.7410

0.93 (0.34–2.60)

0.8961

0.99 (0.42–2.33)

0.9828

3

2.20 (1.27–3.81)

0.0051*

0.62 (0.30–1.29)

0.2005

1.50 (0.82–2.77)

0.1915

4

1.00 (0.54–1.86)

0.9940

2.85 (1.36–5.94)

0.0053*

2.16 (1.13–4.12

0.0199*

  1. aHaplotypes with an estimated frequency under 1% were pooled within the baseline for the purposes of analysis. *Statistically significant comparisons of haplotype frequencies.