|
SNP genotype
|
Disease characteristic (n [%])
|
Odds ratios
|
95% CI
|
P
|
|---|
| | |
Crude
|
Adjusteda
| | |
|---|
|
-313G>A (rs931127; negative/positive nodes)
|
|
GG
|
36 (27.5)/18 (14.5)
|
1.00
|
1.00
| | |
|
GA
|
58 (44.3)/60 (48.4)
|
2.23
|
2.15
|
1.14–4.06
|
0.0083
|
|
AA
|
34 (28.2)/46 (37.1)
| | | | |
|
545C>T (rs3741378; ER positive/ER negative)
|
|
CC
|
166 (78.7)/30 (55.6)
|
1.00
|
1.00
| | |
|
CT
|
39 (18.5)/22 (40.7)
|
2.95
|
2.90
|
1.52–5.48
|
0.0012
|
|
TT
|
6 (2.8)/2 (2.0)
| | | | |
|
545C>T (rs3741378; PR positive/PR negative)
|
|
CC
|
140 (77.8)/54 (65.1)
|
1.00
|
1.00
| | |
|
CT
|
35 (19.4)/26 (31.3)
|
1.88
|
1.86
|
1.05–3.30
|
0.0339
|
|
TT
|
5 (2.8)/3 (3.6)
| | | | |
|
2760G>A (rs746429; negative/positive nodes)
|
|
GG
|
64 (49.6)/41 (32.5)
|
1.00
|
1.00
| | |
|
GA
|
46 (35.7)/65 (51.6)
|
2.04
|
2.05
|
1.23–3.44
|
0.0062
|
|
AA
|
19 (14.7)/20 (20.0)
| | | | |
- aAdjusted analysis models include age at diagnosis. CI confidence interval; ER, estrogen receptor; progesterone receptor.
