From: Spontaneous and therapeutic abortions and the risk of breast cancer among BRCAmutation carriers
Variable | Case subjects (N = 1,694) | Control subjects (N = 1,694) | P value |
---|---|---|---|
Current age (mean) | 49.3 | 48.6 | 0.22 |
Year of birth (mean year) | 1951.2 | 1951.8 | 0.10 |
Mutation, N (%) | |||
BRCA1 | 1,313 (77.5%) | 1,313 (77.5%) | |
BRCA2 | 380 (22.4%) | 380 (22.4%) | |
Country of residence, N (%) | |||
United States | 591 (34.9%) | 591 (34.9%) | |
Canada (excluding Quebec) | 491 (29.0%) | 491 (29.1%) | |
Poland | 439 (25.9%) | 439 (25.9%) | |
Israel | 102 (6.0%) | 102 (6.0%) | |
Norway | 55 (3.2%) | 55 (3.2%) | |
Sweden | 7 (0.4%) | 7 (0.4%) | |
United Kingdom | 6 (0.4%) | 6 (0.4%) | |
Austria | 1 (0.1%) | 1 (0.1%) | |
Italy | 2 (0.1%) | 2 (0.1%) | |
Parityb, mean | 2.2 | 2.2 | |
Oophorectomy | 61 (3.6%) | 109 (6.4%) | 0.0002 |
Oral contraceptive use, N (%) | |||
Ever | 1,002 (59.8%) | 1,009 (60.1%) | 0.89 |
Age at menarche, mean | 12.9 | 13.0 | 0.001 |