Table 2 Comparison of spontaneous abortions among Jewish BRCA mutation carriers (n = 795) and non-carriers (n = 110)
From: Spontaneous and therapeutic abortions and the risk of breast cancer among BRCAmutation carriers
All carriers | BRCA1 | BRCA2 | Non-carriers | |
|---|---|---|---|---|
Age (mean) | 51.5 | 51.1 | 52.8 | 47.6 |
Year of birth (mean) | 1947.8 | 1948.1 | 1946.8 | 1950.5 |
Number of full-term pregnancies | 2.15 | 2.11 | 2.24 | 1.94 |
Number of spontaneous abortions | ||||
Never | 595 (74.8%) | 436 (75.7%) | 154 (73.3%) | 78 (70.9%) |
Ever | 200 (25.2%) | 140 (24.3%) | 56 (26.7%) | 32 (29.1%) |
1 | 140 (17.6%) | 100 (17.4%) | 36 (17.2%) | 27 (24.5%) |
2 | 37 (4.7%) | 26 (4.5%) | 11 (5.2%) | 5 (4.6%) |
3+ | 23 (2.9%) | 14 (2.4%) | 9 (4.3%) | 0 (0.0%) |
Mean | 0.37 | 0.34 | 0.44 | 0.34 |