Table 6 Mutation status of individuals from whom fresh frozen normal and malignant ovarian and breast specimens have been obtained
Type of surgery/tissue | BRCA1 mutation positive | BRCA2 mutation positive | BRCA1/2 mutation negativea | Unknown | Total |
|---|---|---|---|---|---|
Breast | |||||
Prophylactic/tumor | 0 | 0 | 1 | 0 | 1 |
Prophylactic/normal | 18 | 16 | 2 | 39 | 75 |
Cancer/tumor | 9 | 7 | 15 | 13 | 44 |
Cancer/normal | 6 | 5 | 11 | 17 | 39 |
Ovary | |||||
Prophylactic/tumor | 0 | 0 | 0 | 1 | 1 |
Prophylactic/normal | 27 | 26 | 0 | 20 | 73 |
Cancer/tumor | 4 | 0 | 0 | 1 | 5 |
Cancer/normal | 6 | 2 | 0 | 7 | 15 |