Figure 2From: Analysis of cancer risk and BRCA1 and BRCA2mutation prevalence in the kConFab familial breast cancer resourceRelationship between estimated probability and predicted relative frequency or BRCA1 and BRCA2 mutations. Women unaffected at time of interview were ranked in quintiles according to their probability of carrying either a (a) BRCA1 or (b) BRCA2 mutation, as estimated by a batch program implementing the Tyrer-Cuzick algorithm, without input of family or individual mutation status. The proportion of women that tested positive for either a BRCA1 (open bars) or BRCA2 (closed bars) mutation is plotted on the vertical axis.Back to article page