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Figure 2 | Breast Cancer Research

Figure 2

From: Analysis of cancer risk and BRCA1 and BRCA2mutation prevalence in the kConFab familial breast cancer resource

Figure 2

Relationship between estimated probability and predicted relative frequency or BRCA1 and BRCA2 mutations. Women unaffected at time of interview were ranked in quintiles according to their probability of carrying either a (a) BRCA1 or (b) BRCA2 mutation, as estimated by a batch program implementing the Tyrer-Cuzick algorithm, without input of family or individual mutation status. The proportion of women that tested positive for either a BRCA1 (open bars) or BRCA2 (closed bars) mutation is plotted on the vertical axis.

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