Figure 2

Receptor expression and growth. This figure compares normal TDLUs and HELUs for ER-α expression, PR expression, proliferation (Ki67 antigen), apoptosis (TUNEL assay), and colocalization of ER-α and Ki67 in the same cells. ^aAverage proportion score (± SEM) representing the estimated proportion of positive cells (0 = none, 1 < 1/100, 2 = 1/100 to 1/10, 3 = 1/10 to 1/3, 4 = 1/3 to 2/3, and 5 = >2/3). ER, estrogen receptor; HELU, hyperplastic enlarged lobular unit; PR, progesterone receptor; SEM, standard error of the mean; TDLU, terminal duct lobular unit; TUNEL, terminal transferase-mediated dUTP nick end-labeling.