Table 4 Estimated cumulative risks of breast and ovarian cancer in BRCA1 and BRCA2 mutation carriers

From: BRCA1 and BRCA2 mutation predictions using the BOADICEA and BRCAPRO models and penetrance estimation in high-risk French-Canadian families

Age (years)	BRCA1			BRCA2
	BC	OC	BC or OC	BC	OC	BC or OC
30	3	0	4	0.3	0	0.4
40	13	0	14	13	0.2	26
50	20 (0–45)	1 (0–10)	23 (0–48)	21 (0–55)	0.4 (0–2)	35 (0–64)
60	71	38	83	33	49	55
70	72 (0–93)	38 (0–78)	83 (34–96)	75 (0–97)	49 (0–81)	89 (34–98)

Shown are percentage cumulative risks (95% confidence interval). BC, breast cancer; OC, ovarian cancer.

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