BRCA1 and BRCA2 mutation predictions using the BOADICEA and BRCAPRO models and penetrance estimation in high-risk French-Canadian families

Table 1 Summary statistics for the 188 families used in predicting the mutation status of the first screened individual

	Full pedigrees	First- and second-degree relatives only
Mean number of individuals per family	27.9	15.9
Number of BC cases^a	993	612
Number of OC cases	66	54
Number of bilateral BC cases	70	58
Cases with BC and OC	26	12
Number of male BC cases	19	11
Median age at BC diagnosis (years)	51	51
Median age at OC diagnosis (years)	57	58

ISSN: 1465-542X