Cell growth was determined by cell count, as detailed in Materials and methods. aExposure to ibandronate (Iban) and/or 17β-estradiol (E2) for 72 hours. bMean percentages of control values (mean ± SD) from three separate experiments. cStatistical analysis (ANOVA, p < 0.01 versus control) on log transformed data, Tukey post hoc test. dNo significant difference compared with Iban and significantly different from E2.