Effects of ibandronate (Iban) on the stimulation of MCF-7 and IBEP-2 cell growth induced by 17β-estradiol (E2). Cells were incubated with 10-4 M Iban and/or 10-8 M E2 or vehicle (control) for 3 days. Cell growth determination was performed after three days as described in Fig. 1. Asterisks indicate ANOVA p < 0.01 versus control, Tukey post hoc test. NS, not significant.