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Table 4 Correlation of histological and tumor biological factors

From: Prognostic relevance of disseminated tumor cells in the bone marrow and biological factors of 265 primary breast carcinomas

  p-value
  Tumor size LN pos G = 3 ER LA HA BM HER2 HER2F Top IIa Ki67 p53
Tumor size - <0.001 <0.001 0.50 <0.001 0.053 0.063 0.50 0.31 0.09 0.61 0.44
LN pos <0.001 - 0.001 <0.001 <0.001 <0.001 0.29 0.47 0.17 0.16 0.17 0.45
G = 3 <0.001 0.001 - 0.10 0.001 0.90 0.65 0.11 0.8 0.71 0.80 0.17
ER neg 0.50 <0.001 0.10 - <0.001 <0.001 0.85 0.29 0.12 0.026 0.034 0.03
LA <0.001 <0.001 0.001 <0.001 - <0.001 0.38 0.64 0.57 0.441 0.36 0.98
HA 0.053 <0.001 0.90 <0.001 <0.001 - 0.58 0.01 0.66 0.89 0.87 0.39
BM 0.063 0.29 0.65 0.85 0.38 0.58 - 0.82 0.063 0.47 0.86 0.67
HER2 0.50 0.47 0.11 0.29 0.64 0.01 0.82 - <0.001 0.06 0.031 <0.001
HER2F 0.31 0.17 0.80 0.12 0.57 0.66 0.063 <0.001 - 0.45 0.55 0.35
Top IIa 0.09 0.16 0.71 0.026 0.441 0.89 0.47 0.06 0.45 - 0.002 <0.001
Ki67 0.61 0.17 0.80 0.034 0.36 0.87 0.86 0.031 0.55 0.002 - 0.004
P53 0.44 0.45 0.17 0.03 0.98 0.39 0.67 <0.001 0.35 <0.001 0.004 -
  1. BM, bone marrow; ER, estrogen receptor; HA, hemangiosis; HER2 = human epithelial growth factor receptor 2; HER2F, HER2 FISH; LA, lymphangiosis; LN, lymph node; Top IIa = topoisomerase IIα.