Breast Cancer Research

Table 4 Correlation of histological and tumor biological factors

From: Prognostic relevance of disseminated tumor cells in the bone marrow and biological factors of 265 primary breast carcinomas

	p-value
	Tumor size	LN pos	G = 3	ER	LA	HA	BM	HER2	HER2F	Top IIa	Ki67	p53
Tumor size	-	<0.001	<0.001	0.50	<0.001	0.053	0.063	0.50	0.31	0.09	0.61	0.44
LN pos	<0.001	-	0.001	<0.001	<0.001	<0.001	0.29	0.47	0.17	0.16	0.17	0.45
G = 3	<0.001	0.001	-	0.10	0.001	0.90	0.65	0.11	0.8	0.71	0.80	0.17
ER neg	0.50	<0.001	0.10	-	<0.001	<0.001	0.85	0.29	0.12	0.026	0.034	0.03
LA	<0.001	<0.001	0.001	<0.001	-	<0.001	0.38	0.64	0.57	0.441	0.36	0.98
HA	0.053	<0.001	0.90	<0.001	<0.001	-	0.58	0.01	0.66	0.89	0.87	0.39
BM	0.063	0.29	0.65	0.85	0.38	0.58	-	0.82	0.063	0.47	0.86	0.67
HER2	0.50	0.47	0.11	0.29	0.64	0.01	0.82	-	<0.001	0.06	0.031	<0.001
HER2F	0.31	0.17	0.80	0.12	0.57	0.66	0.063	<0.001	-	0.45	0.55	0.35
Top IIa	0.09	0.16	0.71	0.026	0.441	0.89	0.47	0.06	0.45	-	0.002	<0.001
Ki67	0.61	0.17	0.80	0.034	0.36	0.87	0.86	0.031	0.55	0.002	-	0.004
P53	0.44	0.45	0.17	0.03	0.98	0.39	0.67	<0.001	0.35	<0.001	0.004	-

BM, bone marrow; ER, estrogen receptor; HA, hemangiosis; HER2 = human epithelial growth factor receptor 2; HER2F, HER2 FISH; LA, lymphangiosis; LN, lymph node; Top IIa = topoisomerase IIα.

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