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Table 3 Distribution of HER2 immunohistochemistry and fluorescence in situ hybridization

From: Prognostic relevance of disseminated tumor cells in the bone marrow and biological factors of 265 primary breast carcinomas

HER2 IHC HER2 amplification No. of cases % FISH positive
0 Negative 62  
  Positive 10 13.9
1+ Negative 37  
  Positive 9 19.5
2+ Negative 9  
  Positive 7 43.7
3+ Negative 5  
  Positive 10 66.7
  1. Correlation p < 0.001. FISH = fluorescence in situ hybridization; HER2 = human epithelial growth factor receptor 2; IHC = immunohistochemistry.