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Figure 2 | Breast Cancer Research

Figure 2

From: Farnesyl-transferase inhibitor R115,777 enhances tamoxifen inhibition of MCF-7 cell growth through estrogen receptor dependent and independent pathways

Figure 2

DNA fragmentation was determined using flow cytometric analysis. MCF-7 cells were incubated for 5 days with tamoxifen (Tx) and R115,777. Floating and adherent cells were harvested, fixed and their DNA was stained using propidium iodide. Data are shown as the percentage of cells with a sub-G1 DNA content over the total number of cells. Each point is the mean value from 6 × 104 cells, and data are expressed as the mean of three independent experiments. Error bars indicate the standard error of the mean.

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