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Figure 4 | Breast Cancer Research

Figure 4

From: Dehydroepiandrosterone inhibits the progression phase of mammary carcinogenesis by inducing cellular senescence via a p16-dependent but p53-independent mechanism

Figure 4

DHEA and DHEA8354 differentially affect p16, p21, and p53 protein expression: Western blot data of control tumors (lanes 1 to 3) and tumors treated with DHEA (1,000 mg/kg diet) (lanes 4 to 6) as estimated by western blotting. For western blotting, tumors were selected with relatively high values of senescence-associated β-galactosidase (SA-β-Gal)-labelled cells and low values of bromodeoxyuridine-labeled cells.

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