Table 3 Summary of associations between patient characteristics and ductal lavage cellularity
From: Nipple aspiration and ductal lavage in women with a germline BRCA1 or BRCA2 mutation
ICMD ducts | Cell count/ml | Total cell count/specimen | ||||||
|---|---|---|---|---|---|---|---|---|
% | P 1 | Median | Range | P 2 | Median | Range | P 2 | |
Overall | 39 | 600 | 0 to 909,090 | 9481 | 0 to 21,818,160 | |||
FY Status | ||||||||
FY duct | 32 | 1625 | 0 to 909,090 | 30,996 | 0 to 21,818,160 | |||
Non-FY duct | 57 | 0.037 | 0 | 0 to 4959 | <0.001 | 0 | 0 to 173,577 | 0.002 |
Menopausal status | ||||||||
Premenopausal | 28 | 1000 | 0 to 50,000 | 22,000 | 0 to 600,000 | |||
Postmenopausal | 51 | 0.034 | 0 | 0 to 909,090 | 0.044 | 0 | 0 to 21,818,160 | 0.055 |
Previous diagnosis of BC | ||||||||
Previous BC | 31 | 1000 | 0 to 909,090 | 22,000 | 0 to 21,818,160 | |||
No BC | 43 | 0.361 | 390 | 0 to 50,000 | 0.191 | 6000 | 0 to 1,229,667 | 0.189 |
Parity | ||||||||
Parous | 35 | 750 | 0 to 909,090 | 12,000 | 0 to 21,818,160 | |||
Non-parous | 58 | 0.073 | 0 | 0 – 50,000 | 0.395 | 0 | 0 to 600,000 | 0.261 |
Breast feeding | ||||||||
Breast fed | 31 | 1000 | 0 to 909,090 | 15,426 | 0 to 21,818,160 | |||
No breast feeding | 57 | 0.024 | 0 | 0 to 50,000 | 0.091 | 0 | 0 to 600,000 | 0.057 |
BC during study | ||||||||
BC | 20 | 6666 | 0 to 25,850 | 79,992 | 0 to 542,850 | |||
No BC | 40 | 0.645 | 500 | 0 to 909,090 | 0.133 | 7688 | 0 to 21,818,160 | 0.261 |
Cytologic atypia | ||||||||
Mild atypia | 5355 | 84 to 50,000 | 105,870 | 1920 to 1,229,667 | ||||
Severe atypia | 3591 | 1917 to 18,666 | 0.75 | 113,752 | 48,000 to 447,996 | 0.892 | ||
Atypia (mild + severe) | 0 | 4875 | 84 to 50,000 | 105,870 | 1920 to 1,229,667 | |||
No atypia | 50 | <0.001 | 14 | 0 to 909,090 | <0.001 | 174 | 0 to 21,818,160 | <0.001 |