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Figure 4 | Breast Cancer Research

Figure 4

From: Antisense oligonucleotides targeting the progesterone receptor inhibit hormone-independent breast cancer growth in mice

Figure 4

Effects of asPR or RU 486 on PR expression in mammary glands. Immunohistochemical staining for PR in sections of paraffin-embedded mammary glands of mice treated with (a) saline, (b) scPR, (c) asPR, or (d) RU 486 for 5 days. Inset: control, in which no primary antibody was added. Primary antibody: PR polyclonal (C-20; Santa Cruz Biotechnology). The procedure was performed as described in Materials and method. asPR, antisense oligodeoxynucleotides to progesterone receptors; PR, progesterone receptor; scPR, scrambled oligodeoxynucleotides to progesterone receptors.

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