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Table 2 Summary of the associations between clinicopathological parameters and EGFR overexpression and amplification

From: Metaplastic breast carcinomas exhibit EGFR, but not HER2, gene amplification and overexpression: immunohistochemical and chromogenic in situ hybridization analysis

Parameter

EGFR IHC

P

EGFR CISH

P

 

Negative

Overexpression

 

No

Amplified

 

Age (years)

54.2 (13.3)

48.8 (13.3)

>0.05

50.4 (13.7)

48.8 (12.7)

>0.05

Size (cm)

4.0 (3.2)

4.4 (3.1)

>0.05

3.8 (2.9)

5.9 (3.9)

>0.05

Lympho-vascular invasion

No

2

9

>0.05

9

2

>0.05

Yes

2

9

 

7

4

 

Lymph node metastasis at diagnosis

No

3

11

>0.05

10

4

>0.05

Yes

1

5

 

4

2

 
  1. CISH, chromogenic in situ hybridization; EGFR, epidermal growth factor receptor. IHC, immunohistochemistry.