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Table 2 Comparison between characteristics of women enrolled in the multicenter trial and the present study

From: Patterns of reduced nipple aspirate fluid production and ductal lavage cellularity in women at high risk for breast cancer

Characteristic

Average, number, or % (range or proportion)

P

 

Multicenter trial

Post-trial series

 

Age (years)

51.9 (26–81)

48.4 (31–67)

 

Age at menarche (years)

12.6 (7–25)

12.7 (9–17)

 

Age at first birth (years)

25.3 (14–42)

28.4 (18–39)

 

Menopausal status

Unknown for 2%

  

   Premenopausal

45 (227/507)

30.3 (10/33)

 

   Postmenopausal

53 (268/507)

69.7 (23/33)

 

1st-degree relatives with breast cancer

0.5 (0–5)

0.74 (0–3)

 

No. of previous biopsies

1.7 (0–18)

1.1 (0–4)

 

Women with previous atypia (%)

19 (96/507)

10 (3/30)

 

Women with previous breast cancer (%)

57 (291/507)

45 (15/33)

 

BRCA+ women (%)

<1 (3/507)

48.5 (16/33)

<0.001

Women taking SERMs (%)

0

36.4 (12/33)

<0.001

Women with oophorectomy (%)

Unknowna

51.5 (17/33)

 

Racial heritage

   

   White

84

100

 

   African-American

12

0

 

   Asian

2

0

 

   Other

2

0

 
  1. aOophorectomy history was not recorded during the trial, but was determined retrospectively for 10 of 19 subjects who participated at our site.
  2. P values reflecting insignificant associations are not shown. SERM, selective estrogen receptor modulator.