Characteristic | Average, number, or % (range or proportion) | P | |
---|---|---|---|
 | Multicenter trial | Post-trial series |  |
Age (years) | 51.9 (26–81) | 48.4 (31–67) |  |
Age at menarche (years) | 12.6 (7–25) | 12.7 (9–17) |  |
Age at first birth (years) | 25.3 (14–42) | 28.4 (18–39) |  |
Menopausal status | Unknown for 2% | Â | Â |
   Premenopausal | 45 (227/507) | 30.3 (10/33) |  |
   Postmenopausal | 53 (268/507) | 69.7 (23/33) |  |
1st-degree relatives with breast cancer | 0.5 (0–5) | 0.74 (0–3) |  |
No. of previous biopsies | 1.7 (0–18) | 1.1 (0–4) |  |
Women with previous atypia (%) | 19 (96/507) | 10 (3/30) | Â |
Women with previous breast cancer (%) | 57 (291/507) | 45 (15/33) | Â |
BRCA+ women (%) | <1 (3/507) | 48.5 (16/33) | <0.001 |
Women taking SERMs (%) | 0 | 36.4 (12/33) | <0.001 |
Women with oophorectomy (%) | Unknowna | 51.5 (17/33) | Â |
Racial heritage | Â | Â | Â |
   White | 84 | 100 |  |
   African-American | 12 | 0 |  |
   Asian | 2 | 0 |  |
   Other | 2 | 0 |  |