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Table 1 Proportion of subjects with ducts yielding nipple aspirate fluid in multicenter trial and present study

From: Patterns of reduced nipple aspirate fluid production and ductal lavage cellularity in women at high risk for breast cancer

Group

NAF+ women (%)

P

 

Multicenter trial (n = 507)

Post-trial series (n = 33)

 

Overall

427/507 (84)

  

Yale trial site

16/19 (84)

12/33 (36)

0.001

Premenopausal

204/227 (90)

7/10 (70)

 

Postmenopausal

209/268 (78)

5/23 (22)

<0.001

 

P < 0.001

P = 0.02

 

No risk reduction

ND

8/11 (73)

 

Risk reduction

ND

5/22 (23)

 
  

P = 0.009

 

BRCA -

ND

11/17 (65)

 

BRCA +

ND

2/16 (13)

 
  

P = 0. 004

 
  1. The P values in the right hand column reflect comparisons between the multicenter trial and the present series. The P values listed in the two center columns reflect comparisons between the two groups listed immediately above them. NAF, nipple aspirate fluid; ND, not done.