Table 2 Association between XRCC1 and XPD polymorphisms and breast cancer risk
From: XRCC1 and XPDgenetic polymorphisms, smoking and breast cancer risk in a Finnish case-control study
Genotype | Cases (%) | Controls (%) | OR (95% CI)a |
|---|---|---|---|
XRCC1-280 | |||
Arg/Arg | 399 (83.1) | 406 (84.8) | 1.0 |
Arg/His | 78 (16.3) | 70 (14.6) | |
His/His | 3 (0.6) | 3 (0.6) | 1.15 (0.80–1.66)b |
XRCC1-399 | |||
Arg/Arg | 237 (49.5) | 256 (53.6) | 1.0 |
Arg/Gln | 196 (40.9) | 185 (38.7) | 1.24 (0.93–1.65) |
Gln/Gln | 46 (9.6) | 37 (7.7) | 1.39 (0.84–2.29)c |
Arg/Gln + Gln/Gln | 242 (50.5) | 222 (46.4) | 1.26 (0.96–1.66) |
XPD-751 | |||
Lys/Lys | 147 (30.6) | 155 (32.3) | 1.0 |
Lys/Gln | 238 (49.5) | 237 (49.4) | 1.03 (0.76–1.40) |
Gln/Gln | 96 (20.0) | 88 (18.3) | 1.10 (0.74–1.63) |
Lys/Lys+Lys/Gln | 385 (80.0) | 325 (81.7) | 1.0 |
Gln/Gln | 96 (20.0) | 88 (18.3) | 1.08 (0.77–1.53) |