From: XRCC1 and XPDgenetic polymorphisms, smoking and breast cancer risk in a Finnish case-control study
Characteristic | Case/controla | ORb (95% CI) |
---|---|---|
Age at menarche | ||
≤12 | 98/101 | 1.0 |
13–14 | 219/251 | 0.82 (0.59–1.16) |
≥15 | 150/127 | 0.99 (0.68–1.46) |
Age at first full-term pregnancy | ||
Nulliparous | 102/57 | 1.0 |
≤25 | 237/263 | 0.55 (0.38–0.81) |
26–30 | 94/122 | 0.44 (0.29–0.69) |
≥31 | 47/40 | 0.64 (0.36–1.12) |
Number of full-term pregnancies | ||
Nulliparous | 102/57 | 1.0 |
1 | 68/64 | 0.59 (0.36–0.98) |
2 | 141/181 | 0.50 (0.33–0.76) |
3+ | 171/180 | 0.54 (0.36–0.80) |
Waist-to-hip ratio | ||
≤0.91 | 187/236 | 1.0 |
>0.91 | 291/243 | 1.38 (1.06–1.81) |
First-degree family history of breast cancer | ||
No | 424/459 | 1.0 |
Yes | 54/22 | 2.53 (1.48–4.31) |
History of benign breast disease | ||
No | 296/313 | 1.0 |
Yes | 180/167 | 1.33 (1.01–1.75) |
Current alcohol intake | ||
Never | 271/206 | 1.0 |
Once a month or less | 134/187 | 0.74 (0.54–1.01) |
Daily-weekly | 75/89 | 0.87 (0.59–1.29) |
Smoking habits | ||
Never active or passive | 210/182 | 1.0 |
Passive only | 153/169 | 0.78 (0.58–1.06) |
Ever active | 112/130 | 0.91 (0.65–1.28) |
<5 pack-years | 45/63 | 0.75 (0.48–1.16) |
≥5 pack-years | 67/67 | 1.08 (0.72–1.62) |