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Figure 3 | Breast Cancer Research

Figure 3

From: 25-Hydroxyvitamin D31α-hydroxylase expression in breast cancer and use of non-1α-hydroxylated vitamin D analogue

Figure 3

Transcription activity of EB1285 in MCF-7 cells. (a) The chemical structure of the vitamin D analogue EB1285 before and after (EB1089) 1α-hydroxylation. (b) VDR-directed transcription activity of EB1089 or EB1285 in transfected MCF-7 cells. (c) Activation of transcription in the presence of the cytochrome P450 inhibitor ketoconazole. Asterisks represent p < 0.001.

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