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Table 5 Main biological functions among the present 64-gene set and the 70-gene set from the van't Veer study

From: Gene expression profiling spares early breast cancer patients from adjuvant therapy: derived and validated in two population-based cohorts

Biological function 64-gene set (present study) 70-gene set (van't Veer and colleagues)
DNA replication/transcription/nucleosome assembly IGF1, RRM2×2, TOP2A ORC6L, MCM6, RFC4
  PFS2, CENPF, HOXA5, CBFA2T1, SETBP1, UHRF1, MKI67, HIST1H2BG, H2AFZ KIAA1442, CENPA
Cell cycle/proliferation/growth CDKN1C, PTN, CDC2×2, EXT1, HEC, PRC1, NUSAP1 (LOC51203), MCM6, Cyclin E2, TGFB3, FLT1, FGF18, ECT2, GMPS, IGFBP5 × 2, ESM1, WISP1
  BUB1B, ESPL1, PRC1, TOP2A, NUSAP1 (LOC51203), CENPF, IGF1, RHOJ, UHRF1,PDGFD, CBFA2T1, NOV  
Apoptosis ESPL1 FLT1
Cell adhesion/motility/invasion/metastasis SLIT2, COL14A1, FLRT2, MFAP4, CLDN7, IGF1, RHOJ WISP1, FGF18, MMP9
Angiogenesis PTN FLT1
Signal transduction IGF1, RHOJ, EXT1, GNAZ, GFBP5, CFFM4, FGF18, NMU, RAB6B, PK428, PK428 MP1, WISP1, DKFZP564D0462 (GPR126)
  PTN, DNM1, GPR56