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Table 1 Characteristics of patients operated for breast cancer at the Karolinska Hospital 1994–1996

From: Gene expression profiling spares early breast cancer patients from adjuvant therapy: derived and validated in two population-based cohorts

Patient categories All patients (n = 524) No available tissuea (n = 231) Excluded for other reasonsb (n = 134) Included for analysis (n = 159)
Mean age at breast cancer diagnosis (years) 58 57 58 58
Mean tumor size (mm) 20 16 24 22
Proportion of patients with tumor size <21 mm (%) 68 77 57 62
Proportion of patients with positive lymph nodes (%) 26 16 32 38
Proportion deceased (%) 20 12 26 24
  1. aNo frozen tumors in the tumor bank (n = 231).
  2. bLiving abroad (n = 7), actively refused participation (n = 6), degraded tumors (n = 42), insufficient amount of RNA (n = 35), not passed the QC for the arrays (n = 12), profiled on the U95 chip (n = 14), neoadjuvant chemotherapy (n = 12), in situ cancer (n = 5) and stage IV at diagnosis (n = 1).