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Table 1 Putative ESEs in BRCA1

From: Evolutionary conservation analysis increases the colocalization of predicted exonic splicing enhancers in the BRCA1gene with missense sequence changes and in-frame deletions, but not polymorphisms

Exon Length (nt) Predicted SF2/ASF ESEs Predicted SC35 ESEs Predicted SRp40 ESEs Predicted SRp55 ESEs Total predicted ESEs Nucleotides mapping to predicted ESEs ESEs as % of exon
2 80 0 0 1 1 2 13 16.250
3 54 0 0 2 1 3 18 33.333
5 78 2 0 4 2 8 41 52.564
6 89 1 0 3 0 4 22 24.719
7 140 2 3 4 3 12 57 40.714
8 106 4 3 3 1 11 51 48.113
9 46 1 0 0 0 1 7 15.217
10 77 2 1 3 0 6 28 36.364
11 3426 (250) 90 (7) 48 (4) 93 (7) 34 (2) 265 (20) 1405 (106) 41.010 (42.400)
12 89 3 1 2 2 8 44 49.438
13 172 4 3 4 3 14 80 46.512
14 127 4 2 7 2 15 66 51.969
15 191 7 2 6 3 18 105 54.974
16 311 (250) 5 (4) 9 (6) 10 (8) 3 (1) 27 (19) 143 (110) 45.981 (44.000)
17 88 3 4 2 2 11 49 55.682
18 78 3 1 1 1 6 32 41.026
19 41 0 0 0 0 0 0 0.000
20 84 2 4 4 0 10 38 45.238
21 55 1 1 2 0 4 23 41.818
22 74 2 1 2 3 8 40 54.054
23 61 3 3 2 1 9 37 60.656
24 125 6 6 7 3 22 89 71.200
Total 5592 (2355) 145 (61) 92 (45) 162 (74) 65 (31) 464 (211) 2388 (1056) 42.704 (44.841)
  1. Numbers in parentheses refer to those sequences within 125 nucleotides (nt) of the exon end. ESE, exonic splicing enhancer.