Figure 5From: Targeted therapy against Bcl-2-related proteins in breast cancer cellsEffect of treatment of ZR-75-1 cells with antisense Bcl-2 and doxorubicin on the apoptosis-related proteins. Cells were pretreated with 10 μg/ml Lipofectamine alone, or 1.0 μM antisense Bcl-2 oligodeoxynucleotides, for 24 hours. Cells were then cultured in standard medium, after which they were treated with 0.5 μM doxorubicin (DOX) for 6, 12, or 24 hours. Whole cell lysate was then extracted and subjected to Western blotting. The data presented are from more than two independent experiments.Back to article page