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Table 2 SULT1A1 and UGT1A1 allele and genotype frequencies

From: Genetic polymorphisms in human SULT1A1 and UGT1A1 genes associate with breast tumor characteristics: a case-series study

 

Caucasiansa

African-Americansb

 

N c

Frequency

N c

Frequency

Allele

   SULT1A1*1

214

0.704

28

0.636

   SULT1A1*2

87

0.286

9

0.205

   SULT1A1*3

3

0.010

7

0.159

   UGT1A1*33 (TA5)

5

0.015

7

0.140

   UGT1A1*1 (TA6)

221

0.639

25

0.500

   UGT1A1*28 (TA7)

120

0.347

13

0.260

   UGT1A1*34 (TA8)

0

0.000

5

0.100

Genotype

   SULT1A1*1/*1

74

0.487

12

0.545

   SULT1A1*1/*2

66

0.434

1

0.045

   SULT1A1*1/*3

0

0.000

3

0.136

   SULT1A1*2/*2

10

0.066

2

0.091

   SULT1A1*2/*3

1

0.007

4

0.182

   SULT1A1*3/*3

1

0.007

0

0.000

   UGT1A1*33/*33 (TA5/TA5)

2

0.012

0

0.000

   UGT1A1*33/*1 (TA5/TA6)

1

0.006

2

0.080

   UGT1A1*33/*28 (TA5/TA7)

0

0.000

4

0.160

   UGT1A1*33/*34 (TA5/TA8)

0

0.000

1

0.040

   UGT1A1*1/*1 (TA6/TA6)

67

0.387

8

0.320

   UGT1A1*1/*28 (TA6/TA7)

86

0.497

5

0.200

   UGT1A1*1/*34 (TA6/TA8)

0

0.000

2

0.080

   UGT1A1*28/*28 (TA7/TA7)

17

0.098

1

0.040

   UGT1A1*28/*34 (TA7/TA8)

0

0.000

2

0.080

  1. aAllele frequencies were defined in 152 subjects for SULT1A1 and in 173 subjects for UGT1A1.
  2. bAllele frequencies were defined in 22 subjects for SULT1A1 and in 25 subjects for UGT1A1.
  3. cN, number of alleles for allele frequency calculations or number of patients for genotype frequency calculations.