Skip to main content

Table 3 Relationship between COX-2 and MDR1/P-gp (detected with C219 or JSB-1 antibodies) expression (Chi2-Test, P < 0.001)

From: Relationship between the expression of cyclooxygenase 2 and MDR1/P-glycoprotein in invasive breast cancers and their prognostic significance

  COX-2 positive cases COX-2 negative cases Sum
Entire study group (n = 104)    
   C219 low [IRS 0–3] 56 5 61
   C219 high [IRS 4–12] 2 41 43
Sum 58 46 104
   JSB-1 low [IRS 0–3] 55 4 59
   JSB-1 high [IRS 4–12] 3 42 45
Sum 58 46 104
Patients postoperatively treated only with chemotherapy (n = 28)    
   C219 low [IRS 0–3] 13 1 14
   C219 high [IRS 4–12] 1 13 14
Sum 14 14 28
   JSB-1 low [IRS 0–3] 12 1 13
   JSB-1 high [IRS 4–12] 2 13 15
Sum 14 14 28
  1. COX-2, cyclooxygenase-2; MDR1/P-gp, MDR1/P-glycoprotein; IRS, immunoreactive score [17].